What is Invokana?
Invokana is an SLGT-2 inhibitor (sodium-glucose cotransporter 2 inhibitor) with a generic name of canagliflozin. When used with diet and exercise to treat type-2 diabetes mellitus in adults, Canagliflozin can help with glycemic control. It works by decreasing the amount of sugar absorbed by the body and increasing the amount of sugar excreted in the urine.
How is Invokana used?
A starting dose of Canaglifozin 100mg daily is usually prescribed. If needed this can be increased up to a maximum daily dosage of 300mg until glycemix control is achieved.
Invokana tablets should be taken before your first meal of the day.
Each strip of Invokana contains 10 tablets, each of 100mg canagliflozin.
A diabetic plan including diet and exercise can help Invokana achieve best results.
Side effects accociated with the use of canagliflozin include:
- genital mycotic infections
- increased urination
- vulvovaginal pruritus
- abdominal pain
- bone fractures
- higher risk of falls
Canagliflozin is contraindicated in patients who:
- are hypersensitive to canagliflozin or other sodium-glucose cotransporter 2 (SGLT2) inhibitors
- have severe renal impairment or end-stage renal disease
- are on dialysis
Canagliflozin will cause a drop in blood sugar levels which can lead to dizziness, light-headedness or fainting. If you are driving a car or operating machinery while taking canagliflozin, be aware of this.
Alcohol has a can cause hypoglycemia and/or hyperglycemia while taking canagliflozin.
Canagliflozin is Pregnancy Category C. It is unknown if Canagliflozin is passed through breastmilk.
If you have any of the folllwing conditions, tell your doctor before taking canagliflozin.
- kidney or liver problems
- hypertension (high blood pressure)
- hypotension (low blood pressure)
- hypercholestrolemia (high blood cholesterol)
- or high blood levels of potassium
Canagliflozin can interact with other medicines. Some will affect the activity of canagliflozin and canagliflozin will affect some medicines effectiveness. Tell you doctor of all medicines you are taking including prescription drugs and non-prescription drugs before you begin treatment with canagliflozin.