What is Aprezo (Apremilast)
Aprezo (Apremilast) is used for the treatment of various forms of psoriasis
(pustular, non-pustular, drug-induced, etc.), arthritis, which arose as a
complication of psoriasis, plaque psoriasis of moderate or severe degree,
which cannot be treated with other cytostatics (methotrexate, cyclosporitis,
etc.).
Aprezo (Apremilast) Dosage and Administration
Treatment with Aprezo (Apremilast) can be prescribed only by a specialist who
has sufficient experience in the diagnosis and treatment of psoriasis and
psoriatic arthritis. Always follow your doctor`s instructions when using
Aprezo (Apremilast) to get the safest and most effective results from
treatment. The dosage is prescribed by the doctor individually for each
patient. The recommended dose of apremilast is 30 mg orally 2 times a day,
morning and evening, with an interval of about 12 hours. An initial dose
titration is required.
If the patient skips taking the drug, then the next dose should be taken as
soon as possible. If a dose skip is detected immediately before the time of
the next dose, then the missed dose is not taken and proceeds to the next dose
at the appropriate time. The patient SHOULD NOT takes two doses of the drug at
the same time.
The maximum therapeutic effect was observed in the first 24 weeks of
treatment.
Aprezo (Apremilast) Side Effects
The use of Aprezo (Apremilast) may cause side effects in some patients
including:
-
nausea
-
vomiting
-
diarrhea
-
upper respiratory tract infections
-
cough
-
headache
-
decreased appetite
-
insomnia
-
depression
-
rash
-
fatigue
-
backache
-
weight loss
Contact your doctor immediately if you experience any serious or worrying
symptoms.
Aprezo (Apremilast) Warnings and Precautions
Patients with rare hereditary disorders in the form of galactose intolerance,
with congenital lactase deficiency or with malabsorption of glucose-galactose
should not take this drug.
Using during pregnancy
Before starting treatment, it is necessary to exclude pregnancy. Women capable
of childbearing should use an effective method of contraception during
therapy.
Data on the use of Aprezo (Apremilast) in pregnant women are limited. Aprezo
(Apremilast) is contraindicated in pregnancy.
Children
Due to insufficient data on the safety and efficacy of the use of this
medicinal product in this age group, it is not recommended for children (under
18 years of age).
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